In the neuroblastoma cell line, SH-SY5Y, DGKβwas mainly expressed on the plasma membrane (Fig. 8A), consistent with localization of GFP-DGKβ in primary cultured mouse hippocampal neurons (Fig. 6A magnified image) and endogenous DGKβ in primary cultured rat hippocampal neurons [10]. The gene discussed is DGKB; the disease is neuroblastoma.