Remarkably, percentages of CD134 and CD80 expressing CCR6+ cells were significantly increased in patients with SLE in comparison to healthy controls (CD134: 67.87 ± 12.23% vs. 59.27 ± 8.18%, P = 0.02; CD80: 26.46 ± 12.28% vs. 13.86 ± 3.82%, P = 0.001). This evidence concerns the gene CCR6 and systemic lupus erythematosus.