SOD1 and amyotrophic lateral sclerosis: Using the set of rabbit antibodies raised against peptides in the SOD1 sequence, we found small round inclusions in spinal cord motoneurons of all the 29 sporadic and 8 familial ALS patients lacking mutations in the SOD1 gene and in the 2 SBMA patients (Figures 1A, B, D, E and N) and (Supporting Information Figures S1B, E, H and K, and S2A].