Although, it is unknown how RA signals stimulate GATA4/6 expression in this system, previous studies of pluripotent F9 teratocarcinoma cells have identified GATA4 and GATA6 as transcriptional targets of RARγ [68] and RARβ2 [69] signaling complexes, respectively. This evidence concerns the gene GATA6 and teratocarcinoma.