EGFR and lung adenocarcinoma: We found that 42.1% (56/133) of lung adenocarcinomas showed EGFR FISH positivity, and that EGFR FISH positivity was more frequent in late stages than in early stages of lung adenocarcinomas (although no statistically significant difference showed after Bonferroni correction, but there was trend show difference, probably due to the reason of low volume samples).