EGFR and metastatic malignant neoplasm in the lymph nodes: After Bonferroni correction for 5 comparisons, P < 0.01 were considered significant, EGFR mutations were significantly associated with smoking status (non-smoking vs. smoking, p = 0.008), and were not associated with age, gender, lymph node metastasis or tumor stage (p ≥ 0.01) (Table 1).