For each individual epitope, no significant difference (Mann-Whitney Test) was detected between these two groups (Table 4), although there were trends showing that (i) GAD65p70-specific IFNgamma responses were slightly increased in T1D group; (ii) GAD65p15 and GAD65p35-specific IL10 responses were slightly increased in the non-diabetic group. This evidence concerns the gene IL10 and type 1 diabetes mellitus.