RENBP and infection: As we and others observed that memory OT-I cells migrate to the WP 24 hours after the challenge infection in an Ag-dependent fashion (Figure 10, [17]), the only place where these memory OT-I cells may have first encountered their Ag is the RP (though later Ag recognition events in the WP are likely given the relocation of the memory OT-I cells to this zone 24 hrs after the challenge infection).