IL10 and inflammatory bowel disease: Based on these published studies, and on our own observations of only mild inflammation in 12 week old Il10-/- mice (C57 background) that were raised under conventional conditions (M. P. G. Barnett, "unpublished observations"), we decided to establish bacterially-inoculated Il10-/- mice as a model of IBD in order to test food-gene interactions associated with IBD.