TIMP1 and Hepatic fibrosis: Whether combining other known biomarkers of liver fibrosis such as tissue inhibitor of metalloproteinases-1 (TIMP-1), hyaluronic acid (HA), N-terminal propeptide of type III procollagen (PIIINP) or YKL-40 [30,37,38] may increase the sensitivity and specificity of this algorithm needs further studies to confirm.