The therapy with atorvastatin 80 mg was well tolerated: we did not register any case of myopathy, myositis, rhabdomyolysis or statin-related elevation of alanine aminotransferase; creatine phosphokinase and aspartate aminotransferase were elevated in most subjects as a result of myocardial necrosis. This evidence concerns the gene GPT and Myocardial necrosis.