Our finding that deviation from the average CCL3L1 copy number (i.e., < or >4 copies) found in the Japanese population is associated with increased risk of KD is noteworthy because we have previously found that deviation from median copy number of CCL3L1 is also associated with an increased risk of systemic lupus erythematosus (SLE) [37] – a disease with broad immunological underpinnings – in three separate cohorts (TX, USA; Ohio, USA; and Medellin, Colombia). Here, CCL3L3 is linked to systemic lupus erythematosus.