We tested the effect of agonists of TLR2 (P40 protein of Klebsiella pneumoniae and the Pam3Cys lipopeptide), TLR3 (double-stranded RNAs Poly(I∶C)), TLR4 (LPS and lipid A) and TLR7 (R848) on experimental allergic asthma and autoimmune diabetes in the NOD mouse. Here, TLR4 is linked to allergic asthma.