Activating mutations of RAS genes, activation of the PTEN/AKT pathway (due to activating mutations of PIK3CA or loss-of-function mutations of PTEN) [10, 11], or rearrangements of the genes PAX8 and PPAR γon chromosome 2q24 are often found in sporadic FTC [12]. This evidence concerns the gene PTEN and thyroid cancer, nonmedullary, 2.