Mutations found in PKP1, DSG1, PG, or DP give rise to symptoms typical of ectodermal dysplasias, while autoantibodies against desmosomal proteins induce Pemphigus Vulgaris or Pemphigus Foliaceus, accompanied by blisters in the oral mucosa and/or skin [32, 33]. The gene discussed is PKP1; the disease is ectodermal dysplasia syndrome.