Chang et al (2008) first described the conserved promoter regions of both miR-29 family clusters on chromosome 1q32.2 (miR-29b2/c) and chromosome 7q32.3 (miR-29a/b1). They showed that both clusters were suppressed by the oncogenic transcription factor Myc in B-cell lymphoma. Wang et al (2008) proposed that the miR-29b2/c cluster on chromosome 1 is suppressed in rhabdomyosarcoma through NFκB/YY1 via the same conserved upstream promoter region. This evidence concerns the gene MYC and rhabdomyosarcoma.