This translates into a 1.5-fold increase in the specific doxorubicin induced apoptosis (SDA) in the B7-H1 negative cells treated with B7-H1-siRNA inhibitor (Figure 4A top) indicating an anti-apoptotic role of B7-H1 in breast cancer cells (the columns are means and error bars are SEMs). The gene discussed is CD274; the disease is breast cancer.