CD19+CD21low/−CD23low/− B cells numbers and percentages within the B cell gate were expanded in both models by day 8, Balb/c mice experienced further increased numbers and levels measured at d15 post-infection, whereas C57Bl/6 mice did not (p<0.0001, p = 0.002, numbers and percentage of B cells, respectively)(Fig 7C). The gene discussed is CD19; the disease is infection.