Intriguingly, these genes are substantially up-regulated 4 hours after allergen inhalation challenge in Ascaris suum-sensitized monkeys with marked post-challenge eosinophil lung infiltration [26], and CCL18 and CCL13 appear to be up-regulated even in acute or minimally lesional AD skin [27], [16], [25]. The gene discussed is CCL18; the disease is Alzheimer disease.