IL10 and diabetes mellitus: To test whether IL-10 secretion by DNCD3 differentiating splenocytes plays a role in protection against diabetes transfer in NOD/Scid mice, a group of NOD/Scid mice was first infused with TCRγδ/NK-depleted, FACS-sorted DNCD3 splenocytes (5×105 cells/mouse) from 14 day-old NOD females followed by i.v. injection of 4 doses of IL-10 neutralizing Ab (100 μg/mouse every other week).