EPHB4 and colon carcinoma: This response was strongest for ephrin-B1 +EphB2 and ephrin-B1 + EphB3 with the response from ephrin-B1 and EphB4 only producing minor modifications in cell distribution and compartmentalization in the DLD1 colorectal adenocarcinoma and Co115 colon carcinoma cells lines used in that study.