For example, TLR2 signaling has been shown to promote lung cancer cell growth and resistant of apoptosis [11]; TLR3 can directly trigger apoptosis in human cancer cells, such as breast cancer cells [12], TLR2 and TLR9 can promote invasiveness and metastasis through metalloproteases and integrins [13,14]. The gene discussed is TLR2; the disease is breast cancer.