Moreover, during the first few days following the infection, a transient increase (Figure 2B) in blood MO having an inflammatory phenotype CD43- CD62L+ Ly-6C+ was observed (57.2 ± 12.7% of MO on day -1 before infection vs 80 ± 11% on day 3 post-infection; P < 0.03) (the Gr-1 antigen is not expressed on NOD/SCID MO surface). Here, SPN is linked to infection.