NR3C1 and infection: An increase in nuclear EDS1 accumulation either by pathogen infection triggering TIR-NB-LRR activation (Figure 2) or by Dex-induced release of a EDS1-YFP-GR fusion to nuclei accompanying a pathogen stimulus (Figure 6) correlated with the induction or repression of particular host genes (Figures 3 and 7), supporting a role for nuclear EDS1 in driving transcriptional reprogramming during plant defense.