UCP1 and obesity due to melanocortin 4 receptor deficiency: Increased occurrence of brown-like adipocytes within WAT depots is a feature of mouse strains resistant to dietary obesity, such as the A/J strain [31]; [32], and reduced adiposity associated with aP2-transgenic expression of UCP1 is linked to increased energy dissipation in white, but not interscapular brown, adipose tissue [33].