ITIH4 and AIDS: In this regard the recent observations of limited protection against HIV-1 infection, about 31%, in a phase III Thai clinical trial with a combination of a recombinant canarypoxvirus and the protein gp-120, points in the direction that both humoral and cellular immune responses might be needed for protection against HIV/AIDS, although the specific T cell and neutralizing antibody responses in the trial were low [6].