CD34 and neoplasm: Histologically, DFSP should be differentiated from lesions, such as, benign and malignant fibrous histiocytoma, atypical fibrosarcoma, dermatofibrosarcoma, infantile myofibromatosis, nodular fasciitis, keloid, myxoid liposarcoma and neural tumors; all of which may have similar pathological findings.[1, 3, 5, 7–9] Immunohistochemistry using CD34 is a useful marker for differentiation of DFSP and is also helpful in identifying tumor cells at surgical margins when treating recurrent DFSP.