ALB and malaria: In addition, differences in patient population and spectrum of diseases such as malaria and dengue were addressed.[8] Most patients with dengue shock syndrome would respond simply to oxygen and fluid resuscitation, which may not be as aggressive as in septic shock.[9] The fluid management may be different in patients with malaria; one study suggests benefit for the use of albumin.[10] A significant number of children are malnourished who tend to be sicker,[11, 12] and there are concerns about the adverse effects of aggressive fluid therapy in these children.