Comparative diagnostic accuracy of urine albumin:creatinine ratio (ACR) variables for the differential diagnosis of sepsis after ICU admission: For all patients, the area under the ROC curve (AUC) to distinguish sepsis was highest for ACR1 (0.702) followed by ACR2 (AUC 0.612) and ΔACR (AUC 0.681) [Figure 2]. The gene discussed is ALB; the disease is Sepsis.