Interleukin (IL)-12B on chromosome 5q and IL-23R genes on chromosome 1p were identified using GWAS.[43] Using a 25,215 gene-centric SNP platform for discovery and follow-up tag SNP and sequencing, this study confirmed a reported psoriasis-associated SNP in the IL-12B 3' untranslated region (rs3212227) and found a second SNP (rs6887695) located 60 kb upstream. This evidence concerns the gene IL12B and psoriasis.