FGFR2 and neoplasm: Among the four different types of FGFRs, FGFR1 and FGFR2 have been specifically linked to tumour cells (Klint and Claesson-Welsh, 1999; Korc and Friesel, 2009), and bFGF binds to FGFR1 (Ornitz et al, 1996).