SNCG and breast carcinoma: SNCG overexpression in breast cancer cells stimulates proliferation, induces metastasis, promotes chromosomal instability, inhibits mitotic checkpoint [12,17-19], and increases resistance to certain chemotherapeutic or anti-microtubule agents [20,21], however down-regulation of SNCG expression sensitizes breast cancer cells to anti-microtubule agents-induced cytotoxicity [20-22].