Further investigations showed that apoptotic naïve T cells (CD45RA+CD8-caspase3+caspase8+NfkB+) and apoptotic memory T cells (CD45R0+CD8-caspase3+caspase8+NfkB+) are increased in BE compared to the controls and EAC (Figure 3b and 3c). Here, CD8A is linked to Barrett esophagus.