CD163 and systemic sclerosis: However, the number of CD163+ cells and CD204+ cells between the collagen fibers in the skin of SSc patients were significantly greater than that of healthy controls (3.8 ± 0.8 vs 1.2 ± 0.5 and 3.6 ± 0.6 vs 0.4 ± 1.6, respectively; P < 0.05, Table 2).