DES and neoplasm: No association was found between cyclin H status and localisation of the primary tumour (p = 0.471), sex (p = 0.935), and routine immunohistochemical markers such as CD34 (p = 1.000), smooth muscle actin (p = 0.479), desmin (p = 0.564) and Ki-67 (p = 0.227); Table 3.