The combination of cyclin H positivity and high risk GIST showed the strongest predictive p-value for poor disease-free as well as disease-specific survival (p = 0.001 and p < 0.001, log-rank test; cyclin H positive high risk GIST in comparison with the rest of the whole population; see Table 3 and Figure 5 &6). This evidence concerns the gene CCNH and gastrointestinal stromal tumor.