CCNH and gastrointestinal stromal tumor: The disease-specific survival (DSS) of cyclin H positive GIST-patients after 1, 3 and 5 years is approximately 10% below the cyclin H negative cohort (log-rank test, p = 0.189) and within the cyclin H positive GIST patients the disease specific mortality rate is 22% compared to 14% in patients with cyclin H negative GIST (p = 0.369); Table 3.