To address this issue we initially assessed the expression of NF-κB components in B220+ splenic B cells of 4 week-old precancerous Eμ-Myc transgenic mice (n = 5) and their wild type littermate controls (n = 5), and in several (n = 13) Eμ-Myc lymphomas. The gene discussed is NFKB1; the disease is lymphoma.