DNAJC5 and malaria: It was an exciting time: DNA sequences of the Plasmodium falciparum circumsporozoite protein (CSP) identified by Ruth Nussenzweig were being published,22,23 and I began a project with Russell Howard to clone and characterize the sequence of a malaria parasite gene we termed pfhrp2. 24 Sequence information from the CSP gene is used today in the RTS,S recombinant malaria vaccines; and the sequences of PfHRP2 serve as the basis for a number of the rapid diagnostic tests that are now widely deployed for the detection of P. falciparum infection.