GJA1 and neoplasm: Expression of Cx43 is often decreased in human tumor cells and tissues, including those involved in human mammary carcinoma, prostate cancer, human glioblastoma, skin squamous cell carcinoma, lung cancer, esophagus cancer, adrenocortical tumors, ovarian carcinoma, cervical cancer, endometrial carcinoma, and human mesothelioma [27-37].