Firpo et al (2009) also improved the discriminatory power of CA19-9 when used with two acute-phase proteins: haptoglobin and serum amyloid A. In our validation-2 data, ApoC-I levels correlated with white cell count; although ApoC-I is an inflammatory marker, the results confirm those of Takano et al (2008) that ApoC-I is also a potentially useful marker for pancreatic cancer. Here, APOC1 is linked to pancreatic neoplasm.