Cohorts of male control (Brca2F/F), Brca2 heterozygous (Brca2F/+;PBCre4) and Brca2 mutant (Brca2F/F;PBCre4) animals were generated and analysed for tumour progression at 6 months, 10–14 months and 15–20 months of age. This evidence concerns the gene BRCA2 and neoplasm.