In the stromal SP, the top canonical pathways were TREM1 signaling, glucocorticoid receptor signaling, the role of cytokines in mediating communication between immune cells, VDR/RXR activation and the role of pattern recognition receptors in recognition of bacteria and viruses; the main networks implicated were hematological system development and function, cell cycle, cell death, hematological disease, tissue development and cellular and growth proliferation, among others. This evidence concerns the gene VDR and hematologic disorder.