TREM1 and hematologic disorder: In the stromal SP, the top canonical pathways were TREM1 signaling, glucocorticoid receptor signaling, the role of cytokines in mediating communication between immune cells, VDR/RXR activation and the role of pattern recognition receptors in recognition of bacteria and viruses; the main networks implicated were hematological system development and function, cell cycle, cell death, hematological disease, tissue development and cellular and growth proliferation, among others.