In order to analyze the potential inflammatory response to the oral administration of L. plantarum expressing OspA lipoprotein, we performed an assay using monolayer cultures of intestinal epithelial cells (T84), a human colon carcinoma cell line, stimulated with UV-killed LpA and LpAD17 and determined the production of IL-8 (Fig. 4). The gene discussed is CXCL8; the disease is colon carcinoma.