In the present study, to identify novel relationship between E-cadherin and miR-200c in pancreatic cancer, we quantified miR-200c expression in a panel of 14 pancreatic cancer cell lines and in 99 samples of macro-dissected formalin-fixed paraffin-embedded (FFPE) pancreatic tissues. The gene discussed is CDH1; the disease is familial pancreatic carcinoma.