However, despite the fact that Dasatinib, Imatinib, Nilotinib, and Sorafenib inhibit PDGFR with comparable IC50 values ranging from 28 nM - 80 nM [15-17], their effects on proliferation and/or viability of CAF strains from lung carcinomas in vitro were remarkably different. This evidence concerns the gene PDGFRB and lung carcinoma.