EGFR and endometrial cancer: Hec50co cells do, however, express lower levels of both sEGFR and EGFR, and such differences are consistent with previous reports indicating that serum sEGFR levels may be a useful indicator of responsiveness to gefitinib in other cancers, and also with the observation that serum sEGFR is a useful predictor of overall survival in endometrial cancer patients.