Subjects who were heterozygous or homozygous for the variant allele (399Glu) of XRCC1 appeared to experience a higher risk of pterygium than those who were homozygous for the wild-type allele (399Arg) (OR: 1.758; 95% CI: 1.038–2.980, p=0.036; Table 3). The gene discussed is XRCC1; the disease is pterygium.