However, two non-cancerous BRCA1-mutant ovarian epithelial cells (HOSE-642 and HOSE-636) along with BRCA1-mutant ovarian cancer cells (UWB1) revealed a slight and significant increases in cell proliferation (Fig. 5A) at 1, 10 and 100 nM PAF (p < 0.05). The gene discussed is BRCA1; the disease is ovarian cancer.