To investigate whether ovarian epithelial cells with BRCA1-mutation and PAFR-over-expression might be particularly sensitive and responsive to the inflammatory lipid mediators such as PAF, ovarian cancer cells (UWB1) with BRCA1-mutant and over expression of PAFR were treated with PAF (100 nM) for 24 hours, followed by protein phosphorylation detection and profiling using the kinase array. The gene discussed is BRCA1; the disease is ovarian cancer.