BCL2 and renal cell carcinoma: Although the binding capacity of Bim in terms of anti-apoptotic Bcl-2 proteins is broader than that of ABT-737, there is the chance that ABT-737 will nevertheless overcome apoptosis resistance of RCC when combined with other chemotherapeutic drugs, for instance by releasing the little Bim there is from its sequestration to anti-apoptotic Bcl-2 proteins.