Noxa- but not Bim- or Puma-specific siRNA also inhibited cell death induced by the combination of vinblastine and ABT-737 in RCC-26A (Figure 5A) and RCC-30 (Figure 5B; for the comparative expression of Bcl-2 family proteins in RCC-26A and 30 see Additional file 1, Figure S4D). The gene discussed is PMAIP1; the disease is renal cell carcinoma.