CHRNA7 and Cognitive impairment: Several lines of evidence suggest that the α7 subtype of the nicotinic acetylcholine receptors (α7 nAChRs) plays an important role in the mechanism of auditory P50 gating deficits of schizophrenia, and that α7 nAChR agonists are potential therapeutic drugs for the deficient inhibitory processing of the P50 auditory evoked potential that contributes to the cognitive deficits in schizophrenia [7-17].