CHRNA7 and schizophrenia: Considering the high incidence of nausea among patients treated with α7 nAChR agonists (for example, DMXB-A), it is likely that α7 nAChR agonists (for example, tropisetron) with 5-HT3 receptor antagonism will be suitable therapeutic drugs for schizophrenia, since 5-HT3 receptor antagonists are therapeutic drugs for nausea [45].