CHRNA7 and schizophrenia: It has been reported that the α7 nAChR agonist 3-(2,4-dimethoxybenzylidene) anabaseine (DMXB-A) had effects on auditory P50 deficits, attention/vigilance and working memory Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) [36,37] domains in stable and non-smoking patients with schizophrenia [13,14].