WIF1 and posterior cortical atrophy: Ectopic expression of WIF1 in a bone-metastatic PCa cell line PC-3 resulted in up-regulation of epithelial markers (E-cadherin, Keratin-8 and-18) and down-regulation of mesenchymal makers (N-cadherin, Fibronectin and Vimentin) both in vivo and in vitro, suggesting a reversal of EMT.