FLCN and neoplasm: To examine whether the tumorigenic potential of UOK257 cells was affected by wild-type or mutant FLCN, mutant FLCN (UOK257-P and -H255R) and wild-type FLCN-expressing cells (UOK257-2, -3, -4 and -6) were injected subcutaneously with matrigel into athymic nude mice and tumor growth was measured for up to one year.